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Tang NL, Ganapathy V, Wu X, Hui J, Seth P, Yuen PM, Wanders RJ, Fok TF, Hjelm NM: Mutations of OCTN2, an organic cation/carnitine transporter, lead to deficient cellular carnitine uptake in primary carnitine deficiency

However, clinical evidence supporting broad wellness claims remains limited, with most robust data emerging from specific disease or metabolic contexts rather than general population use

Patients typically report increased mental clarity, reduced fatigue, and a sense of physical lightness early in the protocol

148,149,150,151 A randomized, double-blind, placebo-controlled clinical study showed that supplementation of Gln to the low fermentable oligo-monosaccharides and polyols (FODMAP) diet improves irritable bowel syndrome (IBS) symptoms

After a concussion, the brain can become overstimulated, with too much glutamate (a stimulating chemical) and not enough GABA (a natural calming chemical)