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There are several forms of VCID, including: Vascular dementia Vascular cognitive impairment Poststroke dementia Multi-infarct dementia Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) Subcortical vascular dementia (Binswanger's disease) Cerebral amyloid angiopathy Lewy body dementia (LBD) After Alzheimer's and vascular causes, LBD is the next most common cause of dementia

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Activation of AMPK by upstream kinases phosphorylates target enzymes, such as acetyl-coA carboxylase (ACC), leading to inhibition of lipogenic pathways and activation of FA oxidation 22

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Specifically, MGST3 silencing markedly inhibited proliferation and migration of ihESCs and induced cell death, whereas its overexpression conferred a pronounced survival advantage