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This feature has been utilised for numerous applications in cancer therapeutics, including in diagnostics and also as a direct drug delivery system straight to the tumor

Acknowledgements This work was partially supported by National Basic Research Program of China (973 Program

This assay utilizes Ellmans method in which DTNB reacts with the GSH generated from the reduction of GSSG by the GR in a sample to form a yellow product (TNB 2- )

(2) ROS activates NF-B and MAPK signaling pathways, upregulating the expression of MMPs (MMP-13, MMP-3) and inflammatory factors (IL-1, TNF- ), thereby accelerating the degradation of type II collagen (Col-II) and proteoglycans

SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing