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145 In the randomized trial, AE rates were higher in the CyA arm (94%) than in the PPS arm (56%), with three serious AEs in the CyA arm (increased blood pressure, increased serum creatinine) and one serious AE in the PPS arm (gross hematuria)
This dual mechanism allows both expansion of the stem cell pool and directed tissue repair depending on copper availability
Panels A, B, and C show the percentage of surviving hepatocytes for a 15 g dose, for an 18 g dose, and for a 30 g dose for males and females, respectively
198,199 GRP78 (HSP70) contributes to 5-FU resistance in colorectal and ovarian cancer cells by modulating the PI3K/AKT/mTOR and c-Src/LSF/TS signaling pathways