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951 patients were screened for N370S and L444P that had an onset of PD before 51 years of age and it was discovered that 6.7% were carriers for the GBA mutation, which is equivalent to the prevalence of patients with homozygous or heterozygous PARK2 mutations [28,32]

Selected adults may increase to 7.2 mg after at least four weeks at 2.4 mg when additional weight reduction is clinically indicated. The 0.25 mg dose is the starter rather than the maintenance target