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Too many of them cause damage

Figure 4D is reproduced from (Shen, J., 2022) under the CC BY-NC-ND license

doi: 10.1016/j.tifs.2021.06.016 86

This may be due to liver or kidney disease, or certain cancers and blood disorders: The aetiological profile of high serum cobalamin predominantly encompasses severe disease entities for which early diagnosis is critical for prognosis