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Deficiencies in B12 or defects in methionine synthase will result in 5-methyl-THF trapping with the result being the development of megaloblastic anemia due to the block in nucleotide production and the inability of bone marrow erythroblasts to proceed through S-phase of the cell cycle

Design, synthesis, and evaluation of gamma-phosphono diester analogues of glutamate as highly potent inhibitors and active site probes of gamma-glutamyl transpeptidase

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Khan MIR, Jalil SU, Chopra P et al (2021) Role of GABA in plant growth, development and senescence