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However, during apoptosis, the mitochondrial membrane potential is lost and the mitochondrial permeability transition pore (MPTP) remains open, allowing TMRE to escape into the cytoplasm, resulting in a significant reduction of orange-red fluorescence within the mitochondria [44]

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These cells were then exposed to various stress-inducing agents, including menadione to induce oxidative stress, blue light, and pollutants, mimicking real-world environmental challenges

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Evidence for an HLA-DR4-restricted IgG response