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The most successful approach to date focuses on apoptosis, where the combination of the BCL-2 inhibitor venetoclax and hypomethylating agents has improved outcomes for elderly patients with AML or those ineligible for intensive chemotherapy

Therefore, they can consider freezing sperm before treatment to ensure their fertility

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Farnesyltransferase is an enzyme for farnesylation on the cysteine residue of the CAAX motif region of cytosolic RAS protein, resulting in RAS protein association with cellular membranes

It is not available through the NHS or any regulated UK pharmacy