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In a randomised controlled trial published in the European Journal of Nutrition in 2014, Setria glutathione supplementation demonstrated significant increases in glutathione levels showing a 30% rise in whole blood, a 35% increase in red blood cells and a 260% increase in buccal cells

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These findings indicate that ER stress can regulate melanogenesis and activate the innate immune response, aggravating the pathological process of vitiligo

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