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SAMP8 (Senescence Accelerated Mouse) mice overexpress APP resulting in elevated levels of A in the brain

Additionally, VD has been found to interfere with the action of growth factors like insulin-like growth factors (IGF) by promoting the release of IGF binding protein 3 (IGFBP3), which limits the pro-proliferative effects of IGF (65)

These effects were particularly notable in the context of overexpression of miR-339-5p following brain injuries such as bleeds and strokes, underscoring GHK-Cu's potential as a research subject in the context of neurodegeneration

10.3870/j.issn.1672-0741.23.11.001 69 XlL.GyZ.RG.NC

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