While formal clinical trials in humans are limited and the compound is not FDA-approved, early preclinical studies and anecdotal reports suggest it may play a role in supporting the body's natural healing processes
The body will only absorb a small amount of the actual B12 from a pill
In a paper recently published in the Journal of Dental Research (April 2025) , the researchers showed that an anti-senescence therapy or senotherapy, consisting of an enzyme inhibitor called dasatinib and a natural flavonoid plant compound called quercetin, reduced markers of senescence and associated periodontal inflammation and bone loss in lab-dish and animal models
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Serum B12, methylmalonic acid (MMA), homocysteine, and folate levels provide comprehensive baseline assessment