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Activation of this pathway increases the cells ability to neutralize ROS before they can damage proteins, lipids, or DNA

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Glutathione levels may also go down in people who drink large amounts of alcohol or who smoke cigarettes

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De Leo E, Taranta A, Raso R, Polishchuk E, DOria V, Pezzullo M, Goffredo BM, Cairoli S, Bellomo F, Battafarano G, Camassei FD, Del Fattore A, Polishchuk R, Emma F, Rega LR (2023) Genistein improves renal disease in a mouse model of nephropathic cystinosis: a comparison study with cysteamine