Overcoming resistance to BRAF inhibition in BRAF-mutated metastatic melanoma
Traditional Chinese medicine Yisui Tongjing relieved neural severity in experimental autoimmune neuritis rat model
A model of intracellular antigen possibly targeted by non-HLA antibodies is the glutathione S-transferase theta 1 (GSTT1) protein, a member of an enzyme superfamily, involved in cellular detoxification pathways, that represents a barrier against the damaging effects of oxidative stress ( As for other recently described donor-recipient gene polymorphism mismatches, such as the collision genotype at the LIMS1 locus ( In the present study, we retrospectively evaluated donor/recipient GSTT1 genetic profile and the kinetics of GSTT1 antibodies in a population of pediatric, non-sensitized kidney recipients systematically monitored for HLA antibodies throughout the post-transplant period, with the aim of analyzing their role in kidney graft outcome
Micronutrients Micronutrients are essential dietary elements, required to orchestrate a range of physiological functions important for development and maintenance of a healthy brain [92]
Clinical trials involving over 900 human subjects across six randomized, double-blind, placebo-controlled studies confirmed the safety profile
