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If effective, treatments can be repeated annually or as symptoms return, with some patients receiving injections for several years

46 While ID typically causes microcytosis and vitamin B12 and folate deficiencies cause macrocytosis, the co-occurrence of these deficiencies may obscure clinical features and complicate diagnosis, leading to underestimation of the prevalence of iron, vitamin B12 and folate deficiencies

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Given that cancer cells are much more dependent on glutamine than immune cells and that V-9302 does not impair CD8(+) T-cell viability and activation 83 , pharmacological inhibitors of SLC1A5 might have high therapeutic potential