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Benzyl alcohols preservative mechanism involves disruption of bacterial cell membrane lipid bilayer integrity and the aromatic alcohol partitions into bacterial membranes, increasing membrane fluidity and permeability, inhibiting electron transport chain function, and impairing membrane-dependent metabolic processes including nutrient transport and oxidative phosphorylation
While electrostatic repulsion from phosphate group addition is known to disrupt protein-nucleotide interactions 103 , our data indicates that S114 phosphorylation does not alter binding by the nuclear export receptor, XPO-1
Moreover, the cream is designed to work for all skin types, including sensitive skin, without causing irritation
