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J Am Soc Nephrol 15(6):13921401 Lomashvili KA, Garg P, Narisawa S, Millan JL, ONeill WC (2008) Upregulation of alkaline phosphatase and pyrophosphate hydrolysis: potential mechanism for uremic vascular calcification

Pros: Zero visible breast scarring Appealing to patients with scar concerns Cons: Only compatible with saline implants (silicone implants cannot be passed through this route unfilled) Least direct surgical access of all techniques Lower precision for implant positioning Not widely offered

The researchers found that glutathione supplementation led to a significant reduction in disease activity, as measured by various clinical markers