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N Engl J Med 336(16):11311141 Narula J, Pandey P, Arbustini E, Haider N, Narula N, Kolodgie FD, Dal Bello B, Semigran MJ, Bielsa-Masdeu A, Dec GW, Israels S, Ballester M, Virmani R, Saxena S, Kharbanda S (1999) Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy

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Longitudinal studies show that a baseline CNFL threshold of 14.1 mm/mm 2 predicts DN onset within 6 years with 67% sensitivity and 71% specificity [46]

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