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Rarely, acetaminophen may cause serious skin reactions such as acute generalized exanthematous pustulosis (AGEP), Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal

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Upon recruitment to the skin site of infection, they transitioned into inflammatory eosinophils I, characterized by upregulation of Cd274 , Il1rn , Fcgr3 , Hif1a , Nfkb1 and Slc2a3 , a high-affinity glucose transporter (Manolescu et al, 2007)