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Phase II drug metabolizing enzymes

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Published Phase 2 clinical trial data used doses of 1mg, 4mg, 8mg, and 12mg administered weekly via subcutaneous injection

1 H NMR data are presented with the following: Chemical shifts () are reported in ppm relative to residual solvent peaks as internal standards, multiplicity (s = singlet, d = doublet, t = triplet, q = quartet, m = multiplet and br = broad), coupling constants ( J ) in Hz and integration