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By neutralizing free radicals and reactive oxygen species, glutathione helps to reduce oxidative stress in cells

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[10] In contrast, other studies report no significant impact of NAC supplements on glutathione levels

[13] [19] Specifically, the function of GSTs in this role is twofold: to bind both the substrate at the enzyme's hydrophobic H -site and GSH at the adjacent, hydrophilic G-site, which together form the active site of the enzyme