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Some supplements can actually harm the liver if taken improperly

According to our knowledge, there are not such precise investigations with stable isotopes conducted for the other B-vitamins, however a cross-sectional study in age matched (non-supplement users) pregnant, lactating and non-pregnant women with B-vitamin intake within the recommended levels, did not find significant differences among the three groups of women in the 24-hour urinary excretion of vitamin B 6 , riboflavin and vitamin B 12 (Reference Shibata, Fukuwatari and Sasaki33)

[DOI] [Google Scholar] 98.Mar M., Morales A., Colell A., Garca-Ruiz C., Fernndez-Checa J.C

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SNPs in SUOX act as a block (especially if combined with the faster CBS SNP) and may result in a log jam of sulfites, causing reactions