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Also, an analysis by meta-analysis of controlled trials has shown that low-carb diets have a significant impact on BMI, HOMA-IR (insulin resistance), and cholesterol content, especially when interventions last more than four weeks [76]

All mice were approved by the Laboratory Animal Welfare Ethics committee at Harbin Institute of Technology (Approval No: IACUC- 2024138) and conducted in accordance with the Guide for Care and Use of Laboratory Animals and the institutional ethical guidelines for animal experiments