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Under physiological conditions, ROS are primarily generated through a combination of enzymatic and non-enzymatic reactions 46

[108] [109] Studies indicate that gastrointestinal inflammation, food allergies, gluten-related disorders (celiac disease, wheat allergy, non-celiac gluten sensitivity), visceral hypersensitivity, dysautonomia and gastroesophageal reflux are the mechanisms that possibly link both

2014;137(Pt 1):5768

One of the possible mechanisms thought to be related to brain overgrowth is the increased blood concentrations of brain-derived neurotrophic factor (BDNF) in newborns who were later diagnosed with ASD (Hazlett et al., 2011

Treatment begins after provider approval