Genetic factors, stress, smoking, alcohol consumption, UV damage, and nutritional deficiencies affect melanin levels in hair
Arch Neurol 57:14851491 Jensterle M, Herman R, Jane A, Mahmeed WA, Al-Rasadi K, Al-Alawi K, Banach M, Banerjee Y, Ceriello A, Cesur M, Cosentino F, Galia M, Goh SY, Kalra S, Kempler P, Lessan N, Lotufo P, Papanas N, Rizvi AA, Santos RD, Stoian AP, Toth PP, Viswanathan V, Rizzo M (2022) The relationship between Covid-19 and hypothalamicpituitaryadrenal axis: a large spectrum from glucocorticoid insufficiency to excessthe capisco international expert panel
Therefore, they die off
Reactive Oxygen Species (ROS) Attenuation Studies indicate that MT-1mediated cAMP elevation enhances antioxidant defense mechanisms in melanocytes, reducing UV-induced ROS accumulation and oxidative DNA damage through upregulation of superoxide dismutase and catalase activity (Abdel-Malek et al., Endocrine Reviews, 2010)
Can be diluted first with water if using around the eye area, or if you have sensitive skin