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12,13 It is thus hypothesised that, in the presence of DMF, the ability of dendritic cells to properly present auto-antigens, including the aforementioned LL37, to T-lymphocytes is blocked

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This has led to interest in NAC for conditions like systemic lupus erythematosus (SLE), where a small RCT found that NAC (2.4-4.8 g/day) improved disease activity scores and reduced anti-dsDNA antibody levels (Lai et al., Lupus, 2012) [42]