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Researchers with prior experience running individual peptide protocols who understand their personal response patterns

Biomater Sci 8(13):37203729

Although the plasma PLP level significantly increased 2.75-fold compared to the baseline level following a 12-week supplementation of daily 50 mg vitamin B-6, no apparent beneficial effects were demonstrated on oxidative stress and antioxidant capacities in patients with liver cirrhosis in the present study

Neither is licensed by the MHRA for weight management, and they are not part of standard NHS obesity treatment pathways

However, it is important to note that these findings are largely limited to animal studies, and clinical evidence remains scarce