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A systematic review found no clinical safety data beyond a very small case series, emphasizing that the safety profile for chronic use in humans remains uncharacterized

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Reference example: Chang et al., 2011 PMID: 21300818 Reference: Chang et al., 2011 Tendon healing in experimental models PubMed: 4

The documentation requirement for the exception: the procedure note must clearly state that the injection is being performed for postoperative pain management following a named surgical procedure, with the surgical encounter date referenced in the note

2.3 Western blot and antibodies The equal amounts (30 g) of protein lysed from aortic tissue and HUVECs, were separated by SDS-PAGE and then transferred onto polyvinylidene fluoride (PVDF) membranes (Merck Millipore, IPVH00010)