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Anemia from another cause, thyroid disease, iron deficiency, folate deficiency, inflammatory disease, and metabolic contributors can all produce overlapping complaints, as can medication effects, sleep disorders, and neurologic conditions

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Another study (PMID: 24897504) in adults found similarly that antibody levels were lower in a group that received Paracetamol before Hep B vaccines

Yet, this change depends on where your body stores fat, which may vary from another person