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Non-genetic predictors of BMI loss To analyse the dependence of achieved BMI loss on non-genetic factors such as drug type, dosage and time on treatment, we fit the following model: where drugType is an indicator variable that equals 1 for individuals using semaglutide and 0 for tirzepatide, dose represents the dose in milligrams, days treat represents the total days on the relevant drug and : represents an interaction term between two or more variables

doi: 10.1016/j.freeradbiomed.2015.03.022

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The deficiency is not lethal for humans but prevents severe attack of malaria since the oxidative stress released in the erythrocytes renders the milieu hostile for Plasmodium which cannot pursue its growth cycle efficiently