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The glyoxalase pathway (consisting of glyoxalase I and glyoxalase II enzymes) for detoxification of methylglyoxal, a cytotoxic molecule, also requires GSH in the first reaction step

The mechanism involves NAD+-dependent enzymes critical for glucose metabolism

Theres an initial inflammatory phase, a proliferative phase (new cells and blood vessels form), and a remodeling phase (the tissue reorganizes to something like its original state)

doi: 10.1210/en.2006-1035

Another reason why Thymosin Alpha-1 has been seeing a surge in popularity is because it has been shown to have great tolerability and adverse side effects are uncommon