Compounds that can either stabilize NRF2 or inhibit KEAP1, thereby enhancing NRF2's antioxidative response, are under investigation for their potential neuroprotective effects against radiation-induced damage [41]
Vitamin D, which performs endocrine functions, exists in two forms, cholecalciferol (D3) and ergocalciferol (D2) [4, 5]
It has the ability to detoxify the body from heavy metals, dangerous radicals and toxic substances
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Thus, it needs to be cleared out quickly to prevent cell and DNA damage, which can lead to cancerous mutations.[ref] Two well-studied genetic variants have different ways of reaching the same endpoint: ~ an alcohol dehydrogenase (ADH1B) variant that speeds up the conversion to acetaldehyde, thus creating a buildup of acetaldehyde ~ an acetaldehyde dehydrogenase (ALDH2) variant that slows down the conversion from acetaldehyde to acetic acid, again creating a buildup of acetaldehyde
