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Expression of IGF-I, the IGF-I receptor, and an IGF binding protein during myoblast differentiation

Excessive oxidative stress can negatively affect different areas of the body such as the brain, eyes, muscles, and skin

doi:10.1007/s00213-024-06735-1 Richie JP Jr, Nichenametla S, Neidig W, Calcagnotto A, Haley JS, Schell TD, Muscat JE

, 44 , 771-786, doi: Schwarzer, R., Laurien, L., and Pasparakis, M

However, increased contractile activity of skeletal muscle increases ROS generation which causes various physiological and biochemical adaptions such as mitochondrial biogenesis and changes in active myofibres