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HF cells in the morroniside-treated group had more proliferating (Ki67-positive) cells than the control group, especially in the regions of proximal hair matrix and the epidermis

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Univariate analysis To define the effect of drug exposure over 4 weeks and 8 weeks of treatment, linear mixed effects models (using the R package nlme 52 ) were fitted on each metabolite adjusting for age, gender, and HRSD 17 scores at baseline with subjects as random variable

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