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Studies have examined its interaction with growth factor pathways, particularly the FAK-paxillin signaling cascade, which plays a role in cell migration and tissue remodeling

it appears to recapitulate the intracellular signals that exercise generates, including AMPK activation, mitochondrial biogenesis, and GLUT4 upregulation, in tissues that can no longer experience them through movement

10.20982/tqmp.11.1.p037 17 DeviS.PasannaR

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Typically, only one Phase 2 proposal is awarded per Phase 1 award