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Numerous aberrant ALS associated proteins can directly interact with mitochondria, compromising their functioning, for instance mutant SOD1 protein accumulates inside mitochondria and impairs energy-generating complexes

The ~110 residue SRCR domains are predominantly classified by a pattern of either six cysteines (Group A) or eight cysteines (Group B) 2

The reaction process for glutamate formation is glutamine + H 2 O glutamate + NH 3 [169]

Saline-alkali stress poses a serious threat to plant health by disrupting ionic balance, elevating oxidative damage, and impairing cellular functions due to elevated pH levels [37]

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