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Larysz, and M

This matters especially in womens health, where the clinical trust gap is well-documented

10.1016/j.bbagen.2012.11.019 11 BoothJ.BoylandE.SimsP

3.6 Anti-muscular atrophy Muscular atrophy is characterized by disrupted molecular pathways such as non-physiological Hedgehog (Hh) signaling, dysfunctional AKT signaling and dysregulation of ubiquitin-proteasome to overall cellular protein turnover, resulting in upregulated components of the ubiquitin-proteasome pathway, specifically muscle atrophy F-box (MAFbx/atrogin-1) and muscle ring finger 1, that promote proteolytic degradation