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OGT promotes the ferroptosis of chondrocytes in osteoarthritis development via O-GlcNAcylation modification of ACSF2

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References: Senolytic Peptide FOXO4-DRI Selectively Removes Senescent Cells From in vitro Expanded Human Chondrocytes Autologous chondrocyte implantation (ACI) is a procedure used to treat articular cartilage injuries and prevent the onset of post-traumatic osteoarthritis

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Cellular Detoxification Research investigates GSH-conjugation as a phase-II detoxification mechanism for xenobiotics and reactive metabolites, and its role in maintaining mitochondrial integrity