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Despite possessing the HTs pathological presentation, the Hashitoxicosis Variant shares the clinical manifestations of Graves hyperthyroidism

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ATPase activity assays confirmed that coumarin stimulates ATP hydrolysis by P-glycoprotein (P-gp), indicating that coumarin acts as a substrate for it, and the nanoparticles were shown to inhibit P-gp-mediated efflux, enhancing drug retention in cells

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Hypersensitivity: People who have had an allergic reaction to losartan or its components in the past should avoid using the medication