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The underlying mechanism involved thioredoxin 1-induced activation of mTORC1, which facilitated GPX4 synthesis and decreased ferroptosis

It is known for its ability to hold water, acting as a lubricant and shock absorber in our joints

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Treatment also upregulated both the enzymatic activity (SOD, APX, GR, DHAR, and MDHAR) and gene expression of AsA-GSH cycle (Figs

When activated, Nrf2 disassociates from its repressor protein KEAP1 that reacts with oxidative radicals, translocates to the nucleus, binds to antioxidant response element and induces the transcription of defensive genes