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In our study, HF-fed obese rats were successfully established, showing increased fasting blood glucose, fasting insulin and HOMR-IR levels, which were later all downregulated by Met or L-car treatment, as anticipated
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256,257 Additionally, alanyl-tRNA synthetase 2 (AARS2) has been shown to act as a mitochondrial lactyltransferase as well, catalyzing the lactylation of K336 in pyruvate dehydrogenase complex 1 (PDHA1) and K457/8 in carnitine palmitoyltransferase 2 (CPT2) under hypoxic conditions
[] Daily consumption of soy protein isolate (19.2 g/day, 24 mg genistein) for 18 months diminished total testosterone and SHBG levels, while leaving free testosterone unchanged
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