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Similarly, animals with deficiencies in indirect scavengers of ROS, such as sulfiredoxin and metallothionein, are highly susceptible to alcohol-induced hepatic injury 27,31

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As expected, these signals were sensitive to imatinib treatment only in WT-Bcr-Abl-32D cells but not T315I-Bcr-Abl-32D cells, while ponatinib 27 treatment abolished these signals in both cell lines (Supplementary Fig