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In addition, to evaluate changes in the testicular microenvironment after FOXO4-DRI treatment, we assessed levels of several common SASP factors in testis tissue, including IL-1, IL-1, IL-6, IL-10, TNF- and TGF-

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Among these, TNF- production by CGCs can increase senescence of mouse oocytes after ovulation, which may be the cause of oocyte quality decline (106)

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Each compound is always drawn separately and injected separately, even when both are administered in the same session