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Some patients receive weekly infusions initially, followed by maintenance treatments as recommended

While animal studies and short-term human use have not revealed concerning signals, effects from years of use remain entirely unknown

This extended period of efficacy stems from Dihexa's ability to modulate the expression levels of synapse-associated proteins (such as PSD-95, GluA1, etc.), rather than simply stimulating neuronal electrical activity

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Alternating Dihexa with other cognitive research compounds acting through different mechanisms can be an effective protocol design strategy that reduces tolerance risk while maintaining neuroplastic stimulus