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In an ischemic mouse model, lactate was shown to trigger astrogliosis through the activation of Akt and STAT3 signaling pathways, further linking metabolic shifts to astrocyte reactivity 78
In the present study, NO plasma levels were found to be increased after exercise, in accordance with other reports, which show that iNOS activity and NO release are increased with exercise in several tissues [36, 37]
Dharajiya N, Choudhury BK, Bacsi A, Boldogh I, Alam R, Sur S: Inhibiting pollen reduced nicotinamide adenine dinucleotide phosphate oxidase-induced signal by intrapulmonary administration of antioxidants blocks allergic airway inflammation
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