have shown that mechanical load in vivo promotes the production of O 2 in mitochondria of chondrocytes, and the expression of SOD1 and SOD2 in mitochondria decreases, while mitochondrial dysfunction induced by superoxide in mitochondria will further lead to cartilage degeneration (Scott et al., 2010)
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Tenrio MCDS, Graciliano NG, Moura FA, Oliveira ACM, Goulart MOF (2021) N-Acetylcysteine (NAC): impacts on human health
They can ship these cells at room temperature and they're viable for weeks, whereas traditional cells, we've got to keep cryopreserved and ship on dry ice
Subconfluent cell monolayers were inoculated with virus at a multiplicity of infection of 0.1 PFU/cell and incubated at 37C for 48 h