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A CobaSorb test showing a clear increase in holoTC supports a normal uptake, while an increase below a set limit should be taken with some reservation before a conclusion of a permanent impaired uptake of B12 is made

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Because vitamin B12 is found primarily in animal products, people who follow vegetarian or vegan diets are at increased risk of deficiency, says Lauren Manaker, a registered dietitian and owner of Nutrition Now Counseling

A patient in perimenopause will not get the same duration as a twenty-eight-year-old on the same protocol, and that is normal physiology, not a failure of treatment