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Keep the vial upright and allow it to return to room temperature before opening

The active ingredient is: 1 ampoule with 1 ml solution for injection contains: Hydroxocobalamin acetate 1500 g

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Sub-spec marketplace product that started at 0.7% benzyl alcohol instead of 0.9%, or with pH outside the 4.5-7.0 range, doesn't get the full 28-day window even with perfect storage

Because B12 is water-soluble, the NIH Office of Dietary Supplements notes that no tolerable upper intake level has been established excess B12 is excreted by the body rather than accumulating to toxic levels