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Furthermore, using redox-sensitive GFP2 (roGFP2) 9,34,35 as a tool for functional analysis of glutaredoxins, we determined that the inactive monothiol glutaredoxin AtGrxS15 from Arabidopsis thaliana 36 is able to utilize glutathione disulfide (GSSG) but not GSH as a substrate

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Some experimental studies have reported that UA stimulates the synthesis of proinflammatory cytokines such as IL-1 beta, IL-6, IL-8, and TNF-alpha

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The most common side effects relate to injection site reactions, occurring in approximately 5-10% of users