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Fe 2+ , free iron ions, forms an unstable iron pool (LIP) in cells, which is transferred to mitochondria and participates in the formation of iron-dependent protein complexes, iron-sulfur clusters, heme, and other metabolic processes
Delivery and packaging were correct and in line with what we expect for routine lab supplies
Examples include nanoparticles delivering CSF1R inhibitors, TLR agonists, transforming growth factor-beta siRNA or other immunomodulatory agents to tumor-associated macrophages, regulatory T cells or myeloid-derived suppressor cells [78,79,80]
ACS Chem Biol 11 , 742747, (2016)